ATRN O75882

吸引蛋白 (DPPT-L) (Mahogany同源物)

功能描述

参与炎症反应初期免疫细胞聚集，并可能调节趋化因子的趋化活性。可能在调节能量稳态和毛色的黑皮质素信号通路中发挥作用。刺豚鼠的低亲和力受体 (By similarity)。在中枢神经系统正常髓鞘化中起关键作用 (By similarity)。 {ECO:0000250, ECO:0000269|PubMed:9736737}。

组织特异性

Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T-lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes.

亚细胞定位

[Isoform 1]: Cell membrane