V型质子ATP酶亚基e 2 (V-ATPase subunit e 2) (溶酶体9 kDa H(+)-转运ATP酶V0亚基e2) (液泡质子泵亚基e 2)
V型质子ATP酶亚基e 2 (V-ATPase subunit e 2) (溶酶体9 kDa H(+)-转运ATP酶V0亚基e2) (液泡质子泵亚基e 2)
Q8NHE4功能描述
液泡(H+)-ATPase (V-ATPase) V0复合物的亚基，该酶是一种多亚基酶，由水解ATP的外周复合物(V1)和转运质子的膜整合复合物(V0)组成 (By similarity)。V-ATPase负责酸化并维持细胞内区室的pH，在某些细胞类型中，其靶向质膜，负责酸化细胞外环境 (By similarity)。 {ECO:0000250|UniProtKB:Q2KIB5}。
组织特异性
Isoform 1 is expressed at high levels in heart, brain and kidney and also detected in inner ear epithelium, vestibule, testis, epididymis and bladder. Isoform 2 is expressed in heart, kidney, placenta and pancreas. Isoform 2 is not detected in frontal cortex, but is prevalent in all other brain areas.
亚细胞定位
Membrane
关键词