肌浆网/内质网钙ATP酶 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (钙泵 3)
肌浆网/内质网钙ATP酶 3 (SERCA3) (SR Ca(2+)-ATPase 3) (EC 7.2.2.10) (钙泵 3)
Q93084功能描述
这种镁依赖性酶催化与钙转运偶联的ATP水解。将钙离子从细胞质转运至肌浆网/内质网腔。参与肌肉兴奋/收缩相关的钙隔离。 {ECO:0000269|PubMed:11956212, ECO:0000269|PubMed:15028735}。
组织特异性
Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues. Expressed in cell lineages of hematopoietic, epithelial, or embryonic origin and also expressed in several cancer cell lines.
亚细胞定位
Nucleus membrane
关键词