逆转录病毒样天冬氨酸蛋白酶 1 (EC 3.4.23.-) (皮肤特异性逆转录病毒样天冬氨酸蛋白酶) (SASPase) (皮肤天冬氨酸蛋白酶) (TPA诱导型天冬氨酸蛋白酶样蛋白) (TAPS)
逆转录病毒样天冬氨酸蛋白酶 1 (EC 3.4.23.-) (皮肤特异性逆转录病毒样天冬氨酸蛋白酶) (SASPase) (皮肤天冬氨酸蛋白酶) (TPA诱导型天冬氨酸蛋白酶样蛋白) (TAPS)
Q53RT3功能描述
负责丝聚蛋白加工的蛋白酶，对于维持正常的表皮组织结构至关重要。 {ECO:0000269|PubMed:32516568}。
组织特异性
Expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles. In psoriatic skin, expressed throughout the stratum corneum. In ulcerated skin, expressed in the stratum granulosum of intact epidermis but almost absent from ulcerated regions. Expressed in differentiated areas of squamous cell carcinomas but not in undifferentiated tumors.
亚细胞定位
Membrane
关键词