芳基硫酸酯酶K (ASK) (EC 3.1.6.1) (葡萄糖醛酸-2-硫酸酯酶) (EC 3.1.6.18) (Telethon硫酸酯酶)
芳基硫酸酯酶K (ASK) (EC 3.1.6.1) (葡萄糖醛酸-2-硫酸酯酶) (EC 3.1.6.18) (Telethon硫酸酯酶)
Q6UWY0功能描述
催化假底物（如对硝基儿茶酚硫酸酯和对硝基苯硫酸酯）的水解 (PubMed:23986440)。催化硫酸软骨素、肝素和硫酸乙酰肝素的2-O-磺酸-D-葡萄糖醛酸残基上2-硫酸基团的水解 (PubMed:28055182, PubMed:34916232)。对2-磺酸葡萄糖醛酸具有选择性作用，且对2-磺酸艾杜糖醛酸无活性 (PubMed:28055182)。 {ECO:0000269|PubMed:23986440, ECO:0000269|PubMed:28055182, ECO:0000269|PubMed:34916232}。
组织特异性
Expressed at high levels in the placenta and pancreas (PubMed:23986440). Expressed at intermediate levels in the lung, brain, heart, liver and kidney and at low levels in the muscle (PubMed:23986440).
亚细胞定位
Secreted
关键词