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ANO10 Q9NW15

钙激活氯通道-10 (跨膜蛋白16K)

蛋白质信息 (UniProt)

钙激活氯通道-10 (跨膜蛋白16K)

Q9NW15

功能描述

不表现钙激活氯通道 (CaCC) 活性。能抑制ANO1的活性。 {ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:22946059}。

组织特异性

Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain.

亚细胞定位

Cell membrane

关键词

3D-structure Alternative splicing Cell membrane Disease variant Membrane Neurodegeneration Proteomics identification Reference proteome Transmembrane Transmembrane helix