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ANGPT4 Q9Y264

血管生成素-4 (ANG-4) (血管生成素-3) (ANG-3)

蛋白质信息 (UniProt)

血管生成素-4 (ANG-4) (血管生成素-3) (ANG-3)

Q9Y264

功能描述

结合TEK/TIE2,调节ANGPT1信号传导。能诱导TEK/TIE2的酪氨酸磷酸化。促进内皮细胞存活、迁移和血管生成。 {ECO:0000269|PubMed:15284220}。

组织特异性

Highly expressed in the lung with much lower levels found in other tissues.

亚细胞定位

Secreted

关键词

Alternative splicing Angiogenesis Coiled coil Disulfide bond Glycoprotein Proteomics identification Reference proteome Secreted Signal