羊膜蛋白 [裂解为：可溶性羊膜蛋白]
羊膜蛋白 [裂解为：可溶性羊膜蛋白]
Q9BXJ7功能描述
由AMN和CUBN形成的内吞受体的膜结合组分 (PubMed:14576052, PubMed:29402915, PubMed:30523278)。CUBN的正常糖基化和向细胞表面运输所必需 (PubMed:14576052, PubMed:29402915)。由AMN和CUBN形成的复合物是有效吸收维生素B12所必需的 (PubMed:12590260, PubMed:14576052, PubMed:26040326)。肾脏中正常的CUBN介导的蛋白转运所必需 (Probable)。 {ECO:0000269|PubMed:12590260, ECO:0000269|PubMed:14576052, ECO:0000269|PubMed:26040326, ECO:0000269|PubMed:29402915, ECO:0000269|PubMed:30523278, ECO:0000305|PubMed:22631584, ECO:0000305|PubMed:26040326}。
组织特异性
Detected in proximal tubules in the kidney cortex (at protein level) (PubMed:14576052, PubMed:29402915). Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes.
亚细胞定位
[Isoform 1]: Apical cell membrane
关键词