AGR2 O95994

前梯度蛋白2同源物 (AG-2) (hAG-2) (HPC8) (分泌性粘附腺蛋白XAG-2同源物)

功能描述

为MUC2的转录后合成和分泌所必需。可能在小肠细胞产生粘液中发挥作用 (By similarity)。原癌基因，可能在细胞迁移、细胞分化和细胞生长中发挥作用。促进细胞粘附 (PubMed:23274113)。 {ECO:0000250, ECO:0000269|PubMed:18199544, ECO:0000269|PubMed:23274113}。

组织特异性

Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines.

亚细胞定位

Secreted