ADAMTS9 Q9P2N4

含血小板反应蛋白基序的解整合素金属蛋白酶9 (ADAM-TS 9) (ADAM-TS9) (ADAMTS-9) (EC 3.4.24.-)

功能描述

裂解大分子聚集蛋白聚糖，aggrecan（在'1838-Glu-|-Ala-1839'位点）和versican（在'1428-Glu-|-Ala-1429'位点）。具有不依赖蛋白酶的功能，促进多种分泌货物从内质网向高尔基体转运。 {ECO:0000269|PubMed:12514189, ECO:0000269|PubMed:22419820}。

组织特异性

Highly expressed in all fetal tissues. Expressed in a number of adult tissues with highest expression in heart, placenta and skeletal muscle.

亚细胞定位

Secreted, extracellular space, extracellular matrix