ADAM28 Q9UKQ2

解整合素与金属蛋白酶结构域包含蛋白 28 (ADAM 28) (EC 3.4.24.-) (附睾金属蛋白酶样、解整合素样及富含半胱氨酸蛋白 II) (eMDC II) (金属蛋白酶样、解整合素样及富含半胱氨酸蛋白 L) (MDC-L)

功能描述

可能在淋巴细胞游出期间发生的粘附和蛋白水解事件中发挥作用，或者可能在淋巴细胞表面靶蛋白（如FASL和CD40L）的胞外域脱落中发挥功能。可能参与精子成熟。

组织特异性

Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.

亚细胞定位

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.