肌动蛋白相关蛋白T1 (ARP-T1)
肌动蛋白相关蛋白T1 (ARP-T1)
Q8TDG2功能描述
负向调节Hedgehog (SHH)信号。结合SHH信号介导因子GLI1的启动子,并抑制其表达。{ECO:0000269|PubMed:28869610}。
组织特异性
In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen.
亚细胞定位
Cytoplasm, cytoskeleton
关键词