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ACTRT1 Q8TDG2

肌动蛋白相关蛋白T1 (ARP-T1)

蛋白质信息 (UniProt)

肌动蛋白相关蛋白T1 (ARP-T1)

Q8TDG2

功能描述

负向调节Hedgehog (SHH)信号。结合SHH信号介导因子GLI1的启动子,并抑制其表达。{ECO:0000269|PubMed:28869610}。

组织特异性

In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen.

亚细胞定位

Cytoplasm, cytoskeleton

关键词

Cytoplasm Cytoplasmic vesicle Cytoskeleton Nucleus Proteomics identification Reference proteome Transcription Transcription regulation