AAMP Q13685

血管相关迁移细胞蛋白

功能描述

在血管生成和细胞迁移中发挥作用。在平滑肌细胞迁移中，可能通过RhoA通路起作用。 {ECO:0000269|PubMed:10329261, ECO:0000269|PubMed:18634987}.

组织特异性

Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics.

亚细胞定位

Cell membrane. Cytoplasm.