ZFYVE26 Q68DK2

含FYVE结构域锌指蛋白26 (含FYVE结构域中心体蛋白) (FYVE-CENT) (Spastizin)

功能描述

磷脂酰肌醇3-磷酸结合蛋白，为胞质分裂中的切割步骤所必需：在胞质分裂过程中被招募至中间体，并作为切割的调节因子。可能也为有效的同源重组DNA双链断裂修复所必需。 {ECO:0000269|PubMed:20208530}。

组织特异性

Strongest expression in the adrenal gland, bone marrow, adult brain, fetal brain, lung, placenta, prostate, skeletal muscle, testis, thymus, and retina. Intermediate levels are detected in other structures, including the spinal cord.

亚细胞定位

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome