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ZFAT Q9P243

ZFAT锌指蛋白 (AITD易感区锌指基因) (锌指蛋白406)

蛋白质信息 (UniProt)

ZFAT锌指蛋白 (AITD易感区锌指基因) (锌指蛋白406)

Q9P243

功能描述

可能参与转录调控。过表达导致许多参与免疫反应的基因下调。一些基因也被上调(通过相似性)。{ECO:0000250}。

组织特异性

Isoform 1 is strongly expressed in placenta, spleen, kidney, testis and peripheral blood leukocytes. Expressed in CD4+ and CD8+ T-cells, CD19+ B-cells and CB14+ monocytes. Isoform 3 is strongly expressed in placenta, ovary, tonsil, CD19+ B-cells and CD14+ monocytes.

亚细胞定位

Nucleus

关键词

3D-structure Alternative splicing Cytoplasm DNA-binding Metal-binding Nucleus Proteomics identification Reference proteome Repeat Transcription