XPNPEP1 Q9NQW7

Xaa-Pro氨肽酶1 (EC 3.4.11.9) (氨酰脯氨酸氨肽酶) (胞质氨肽酶P) (可溶性氨肽酶P) (sAmp) (X-Pro氨肽酶1) (X-脯氨酰氨肽酶1，可溶性)

蛋白质信息 (UniProt)

Xaa-Pro氨肽酶1 (EC 3.4.11.9) (氨酰脯氨酸氨肽酶) (胞质氨肽酶P) (可溶性氨肽酶P) (sAmp) (X-Pro氨肽酶1) (X-脯氨酰氨肽酶1，可溶性)

Q9NQW7

功能描述

金属氨基肽酶，催化从肽的N末端切除倒数第二个脯氨酰残基，例如Arg-Pro-Pro (PubMed:11106490, PubMed:18515364, PubMed:35165443)。参与缓激肽的降解 (PubMed:11106490)。 {ECO:0000269|PubMed:11106490, ECO:0000269|PubMed:18515364, ECO:0000269|PubMed:35165443}。

组织特异性

Expressed in all tissues tested, including pancreas, heart, muscle, kidney, liver, lung and brain. Highest levels in pancreas.

亚细胞定位

Cytoplasm, cytosol

关键词

3D-structure Acetylation Alternative splicing Aminopeptidase Cytoplasm Direct protein sequencing Hydrolase Manganese Metal-binding Metalloprotease

外部链接

UniProt: Q9NQW7

NCBI Gene

GeneCards