Wnt-2b蛋白 (Wnt-13蛋白)
Wnt-2b蛋白 (Wnt-13蛋白)
Q93097功能描述
七次跨膜受体frizzled家族成员的配体。在经典Wnt/β-catenin信号通路中发挥作用。在胚胎肺发育中发挥冗余作用。 {ECO:0000250|UniProtKB:O70283}。
组织特异性
Isoform 1 is expressed in adult heart, brain, placenta, lung, prostate, testis, ovary, small intestine and colon. In the adult brain, it is mainly found in the caudate nucleus, subthalamic nucleus and thalamus. Also detected in fetal brain, lung and kidney. Isoform 2 is expressed in fetal brain, fetal lung, fetal kidney, caudate nucleus, testis and cancer cell lines.
亚细胞定位
Secreted, extracellular space, extracellular matrix
关键词