返回首页

WFDC2 Q14508

WAP四硫键核心结构域蛋白2 (附睾分泌蛋白E4) (主要附睾特异性蛋白E4) (推定蛋白酶抑制剂WAP5)

蛋白质信息 (UniProt)

WAP四硫键核心结构域蛋白2 (附睾分泌蛋白E4) (主要附睾特异性蛋白E4) (推定蛋白酶抑制剂WAP5)

Q14508

功能描述

广谱蛋白酶抑制剂。 {ECO:0000269|PubMed:23139753}.

组织特异性

Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis.

亚细胞定位

Secreted

关键词

Alternative splicing Aspartic protease inhibitor Disease variant Disulfide bond Glycoprotein Protease inhibitor Proteomics identification Reference proteome Repeat Secreted