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VSIG4 Q9Y279

V-set和免疫球蛋白结构域包含蛋白4 (Protein Z39Ig)

蛋白质信息 (UniProt)

V-set和免疫球蛋白结构域包含蛋白4 (Protein Z39Ig)

Q9Y279

功能描述

吞噬受体，T细胞增殖和IL2产生的强负调节因子。替代补体途径转化酶的有效抑制剂。 {ECO:0000269|PubMed:17016562, ECO:0000269|PubMed:17051150}。

组织特异性

Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages.

亚细胞定位

Membrane

关键词

3D-structure Alternative splicing Complement alternate pathway Direct protein sequencing Disulfide bond Immunity Immunoglobulin domain Innate immunity Membrane Proteomics identification

外部链接

UniProt: Q9Y279
NCBI Gene