UNC45B Q8IWX7

Unc-45同源蛋白B (Unc-45B) (SMUNC45)

蛋白质信息 (UniProt)

Unc-45同源蛋白B (Unc-45B) (SMUNC45)

Q8IWX7

功能描述

作为HSP90的共伴侣，是肌球蛋白马达结构域正确折叠所必需的。在肌细胞发育过程中参与肌节形成。是正常早期晶状体发育所必需的。 {ECO:0000250|UniProtKB:Q6DGE9, ECO:0000250|UniProtKB:Q8CGY6}。

组织特异性

Expressed in eye lens tissues. Expressed in muscle (at protein level) (PubMed:33217308).

亚细胞定位

Cytoplasm, myofibril, sarcomere, Z line

关键词

Alternative splicing Cataract Chaperone Cytoplasm Developmental protein Differentiation Disease variant Myofibrillar myopathy Myogenesis Proteomics identification

外部链接

UniProt: Q8IWX7

NCBI Gene

GeneCards