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UGP2 Q16851

UTP--葡萄糖-1-磷酸尿苷酰转移酶 (EC 2.7.7.9) (UDP-葡萄糖焦磷酸化酶) (UDPGP) (UGPase)

蛋白质信息 (UniProt)

UTP--葡萄糖-1-磷酸尿苷酰转移酶 (EC 2.7.7.9) (UDP-葡萄糖焦磷酸化酶) (UDPGP) (UGPase)

Q16851

功能描述

UTP--葡萄糖-1-磷酸尿苷酰转移酶,催化葡萄糖-1-磷酸转化为UDP-葡萄糖,后者是糖原生成的关键前体。 {ECO:0000269|PubMed:31820119, ECO:0000269|PubMed:8354390, ECO:0000269|PubMed:8631325}。

组织特异性

Highly expressed in various brain regions. Expressed in amygdala, anterior cingulate cortex, caudate, cerebellar hemisphere, cerebellum, cortex, frontal cortex, hippocampus, hypothalamus, nucleus accumbens, putamen, spinal cord and substantia nigra (PubMed:31820119). Also widely expressed among other tissues, including liver, heart, placenta, lung, kidney, pancreas and skeletal muscle (PubMed:8354390, PubMed:8631325).

亚细胞定位

Cytoplasm

关键词

3D-structure Acetylation Alternative splicing Cytoplasm Disease variant Epilepsy Magnesium Metal-binding Nucleotidyltransferase Phosphoprotein