TRIM68 Q6AZZ1

E3泛素蛋白连接酶TRIM68 (EC 2.3.2.27) (环指蛋白137) (RING型E3泛素转移酶TRIM68) (SSA蛋白SS-56) (SS-56) (含三方模体蛋白68)

功能描述

具有泛素E3连接酶功能。作为雄激素受体 (AR) 的共激活因子，取决于其泛素连接酶活性。 {ECO:0000269|PubMed:18451177}。

组织特异性

Widely expressed. Expressed at high levels in prostate cancer cell lines. Up-regulation could be restricted to androgen-dependent cells.

亚细胞定位

Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.