TRAPPC6B Q86SZ2

运输蛋白颗粒复合体亚基6B (TRAPP复合体亚基6B)

蛋白质信息 (UniProt)

运输蛋白颗粒复合体亚基6B (TRAPP复合体亚基6B)

Q86SZ2

功能描述

运输蛋白颗粒（TRAPP）复合物的组分，可能在细胞器间运输的特定阶段发挥作用 (PubMed:16025134, PubMed:16828797)。具体参与神经回路的早期发育，可能通过控制与神经元分化和存活调节有关的细胞内钙瞬变的频率和幅度 (Probable)。 {ECO:0000269|PubMed:16025134, ECO:0000269|PubMed:16828797, ECO:0000305|PubMed:28626029}。

组织特异性

Both isoforms are expressed ubiquitously (at transcript level), isoform 1 being the most predominant (PubMed:28626029). Expressed in the fetal brain and different regions of the adult brain and spinal cord (PubMed:28626029).

亚细胞定位

Golgi apparatus, cis-Golgi network

关键词

3D-structure Alternative splicing Disease variant Endoplasmic reticulum Epilepsy Golgi apparatus Intellectual disability Neurogenesis Proteomics identification Reference proteome

外部链接

UniProt: Q86SZ2

NCBI Gene

GeneCards