翻译控制肿瘤蛋白 (TCTP) (Fortilin) (组胺释放因子) (HRF) (p23)
翻译控制肿瘤蛋白 (TCTP) (Fortilin) (组胺释放因子) (HRF) (p23)
P13693功能描述
参与钙结合和微管稳定 (PubMed:12167714, PubMed:15162379, PubMed:15958728)。作为TSC22D1介导的细胞凋亡的负调控因子，通过与TSC22D1蛋白相互作用并使其不稳定发挥作用 (PubMed:18325344)。 {ECO:0000269|PubMed:12167714, ECO:0000269|PubMed:15162379, ECO:0000269|PubMed:15958728, ECO:0000269|PubMed:18325344}。
组织特异性
Found in several healthy and tumoral cells including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas, and lymphomas. It cannot be detected in kidney and renal cell carcinoma (RCC). Expressed in placenta and prostate.
亚细胞定位
Cytoplasm
关键词