滋养层糖蛋白 (5T4 癌胚抗原) (5T4 癌胚滋养层糖蛋白) (5T4 癌滋养层糖蛋白) (M6P1) (Wnt激活抑制因子1) (WAIF1)
滋养层糖蛋白 (5T4 癌胚抗原) (5T4 癌胚滋养层糖蛋白) (5T4 癌滋养层糖蛋白) (M6P1) (Wnt激活抑制因子1) (WAIF1)
Q13641功能描述
可能作为Wnt/β-catenin信号通路的抑制剂发挥作用，通过间接与LRP6相互作用并阻断Wnt3a依赖的LRP6内化。 {ECO:0000269|PubMed:22100263}。
组织特异性
Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.
亚细胞定位
Cell membrane
关键词