TNFSF13 O75888

肿瘤坏死因子配体超家族成员13 (增殖诱导配体) (APRIL) (TNF和APOL相关白细胞表达配体2) (TALL-2) (TNF相关死亡配体1) (TRDL-1) (CD抗原CD256)

蛋白质信息 (UniProt)

肿瘤坏死因子配体超家族成员13 (增殖诱导配体) (APRIL) (TNF和APOL相关白细胞表达配体2) (TALL-2) (TNF相关死亡配体1) (TRDL-1) (CD抗原CD256)

O75888

功能描述

结合TNFRSF13B/TACI和TNFRSF17/BCMA的细胞因子。在肿瘤细胞生长的调节中起作用。可能参与单核细胞/巨噬细胞介导的免疫过程。 {ECO:0000269|PubMed:10973284}。

组织特异性

Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.

亚细胞定位

Secreted

关键词

3D-structure Alternative splicing Cleavage on pair of basic residues Cytokine Disulfide bond Glycoprotein Immunity Proteomics identification Reference proteome Secreted

外部链接

UniProt: O75888

NCBI Gene

GeneCards