TMEM98 Q9Y2Y6

跨膜蛋白98 (Protein TADA1)

功能描述

在少突胶质细胞分化和髓鞘形成中作为MYRF的负调控因子。与MYRF的C端相互作用，抑制MYRF的自剪切和N片段核转位。分泌形式促进T辅助细胞1 (Th1)的分化。 {ECO:0000250|UniProtKB:Q91X86}。

组织特异性

Widely expressed with high expression in the ovary, pancreas and prostate (PubMed:25946230). Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina (PubMed:24852644). Expressed by activated peripheral blood mononuclear cells (PubMed:25946230).

亚细胞定位

Cell membrane