TINAGL1 Q9GZM7

肾小管间质性肾炎抗原样蛋白 (糖皮质激素诱导蛋白 5) (氧化LDL应答基因2蛋白) (OLRG-2) (肾小管间质性肾炎抗原相关蛋白) (TIN Ag相关蛋白) (TIN-Ag-RP)

功能描述

可能与肾上腺皮质分区以及肾上腺皮质细胞中抑制CYP11B1基因表达的机制有关。这是一种非催化性肽酶C1家族蛋白（根据相似性）。{ECO:0000250}。

组织特异性

Highly expressed in aorta, heart, placenta, kidney and a colorectal adenocarcinoma cell line. Moderately expressed in skeletal muscle, pancreas, lung, lymph nodes, adrenal gland, bone marrow and thyroid. Weakly expressed in colon, small intestine, ovary, spleen, testis and prostate. Predominantly found in vascular smooth muscle cells, but also in cardiac and skeletal muscle cells as well as kidney.

亚细胞定位

Secreted