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TFR2 Q9UP52

转铁蛋白受体蛋白2 (TfR2)

蛋白质信息 (UniProt)

转铁蛋白受体蛋白2 (TfR2)

Q9UP52

功能描述

以非铁依赖性方式介导转铁蛋白结合铁的细胞摄取。可能参与铁代谢、肝细胞功能和红细胞分化。

组织特异性

Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly.

亚细胞定位

Cell membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Isoform Beta]: Cytoplasm

关键词

Alternative splicing Cell membrane Cytoplasm Disease variant Disulfide bond Glycoprotein Membrane Proteomics identification Receptor Reference proteome