T细胞白血病/淋巴瘤蛋白1A (癌基因 TCL-1) (癌基因 TCL1) (蛋白 p14 TCL1)
T细胞白血病/淋巴瘤蛋白1A (癌基因 TCL-1) (癌基因 TCL1) (蛋白 p14 TCL1)
P56279功能描述
增强AKT1、AKT2和AKT3的磷酸化和激活。促进AKT1的核转位。增强细胞增殖，稳定线粒体膜电位并促进细胞存活。 {ECO:0000269|PubMed:10716693, ECO:0000269|PubMed:10983986, ECO:0000269|PubMed:11707444, ECO:0000269|PubMed:11839817}.
组织特异性
Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
亚细胞定位
Cytoplasm
关键词