SRC激酶信号抑制因子1 (SNAP-25相互作用蛋白) (SNIP) (p130Cas相关蛋白) (p140Cap)
SRC激酶信号抑制因子1 (SNAP-25相互作用蛋白) (SNIP) (p130Cas相关蛋白) (p140Cap)
Q9C0H9功能描述
作为SRC的负调控因子，通过激活CSK抑制SRC活性及下游信号传导，导致细胞铺展和迁移受损。调节树突棘形态。参与钙依赖性胞吐作用。可能在神经递质释放或突触维持中发挥作用。 {ECO:0000269|PubMed:14657239, ECO:0000269|PubMed:17525734, ECO:0000269|PubMed:19146815}.
组织特异性
Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue.
亚细胞定位
Cytoplasm
关键词