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SPAG11B Q08648

精子相关抗原11B (人类附睾特异性蛋白2) (He2) (蛋白EP2) (精子抗原HE2)

蛋白质信息 (UniProt)

精子相关抗原11B (人类附睾特异性蛋白2) (He2) (蛋白EP2) (精子抗原HE2)

Q08648

功能描述

对大肠杆菌具有抗菌活性 (By similarity)。在雄性生殖道的防御反应中发挥作用,有助于精子的成熟、储存和保护 (By similarity)。 {ECO:0000250|UniProtKB:Q8VBV2}。

组织特异性

Specifically expressed in caput and proximal corpus of epididymis (at protein level) (PubMed:8167223). Present in the epididymal epithelium and on the sperm surface, with a subacrosomal equatorial distribution on the sperm head (at protein level) (PubMed:8167223).

亚细胞定位

Secreted

关键词

Alternative splicing Antibiotic Antimicrobial Defensin Glycoprotein Proteomics identification Reference proteome Secreted Signal