SORBS1 Q9BX66

索宾和含SH3结构域蛋白1 (Ponsin) (SH3结构域蛋白5) (SH3P12) (c-Cbl相关蛋白) (CAP)

功能描述

通过将CBL连接到胰岛素受体，在CBL的酪氨酸磷酸化中发挥作用。胰岛素刺激的葡萄糖转运所必需。参与肌动蛋白应力纤维和粘着斑的形成 (By similarity)。 {ECO:0000250|UniProtKB:Q62417}。

组织特异性

Detected in skeletal muscle (at protein level). Widely expressed with highest levels in heart and skeletal muscle.

亚细胞定位

Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus