SLITRK2 Q9H156

SLIT和NTRK样蛋白2

功能描述

参与突触发生并促进兴奋性突触分化 (PubMed:27273464, PubMed:27812321, PubMed:35840571)。抑制神经突生长 (By similarity)。参与NTRK2的负调控 (PubMed:35840571)。 {ECO:0000250|UniProtKB:Q810C0, ECO:0000269|PubMed:27273464, ECO:0000269|PubMed:27812321, ECO:0000269|PubMed:35840571}。

组织特异性

Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.

亚细胞定位

Membrane