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SLC7A3 Q8WY07

阳离子氨基酸转运蛋白3 (CAT-3) (CAT3) (阳离子氨基酸转运蛋白y+) (溶质载体家族7成员3)

蛋白质信息 (UniProt)

阳离子氨基酸转运蛋白3 (CAT-3) (CAT3) (阳离子氨基酸转运蛋白y+) (溶质载体家族7成员3)

Q8WY07

功能描述

介导阳离子L-氨基酸(如L-精氨酸、L-赖氨酸和L-鸟氨酸)摄取的单向转运蛋白 (PubMed:11591158)。该转运不依赖钠离子和pH,具有适度的反向刺激作用,并通过被动扩散进行 (PubMed:11591158)。 {ECO:0000269|PubMed:11591158}。

组织特异性

Highly expressed in thymus, uterus and testis (PubMed:11591158). Detected at lower levels in brain, mammary gland, prostate, salivary gland and fetal spleen (PubMed:11591158). In brain, highest expression in thalamus, hippocampus and amygdala (PubMed:11591158).

亚细胞定位

Cell membrane; Multi-pass membrane protein.

关键词

Amino-acid transport Cell membrane Glycoprotein Membrane Phosphoprotein Proteomics identification Reference proteome Transmembrane Transmembrane helix Transport