SLC6A8 P48029

钠和氯依赖性肌酸转运蛋白 1 (CT1) (肌酸转运蛋白 1) (溶质载体家族 6 成员 8)

蛋白质信息 (UniProt)

钠和氯依赖性肌酸转运蛋白 1 (CT1) (肌酸转运蛋白 1) (溶质载体家族 6 成员 8)

P48029

功能描述

肌酸:钠同向转运蛋白，介导肌酸的摄取 (PubMed:17465020, PubMed:22644605, PubMed:25861866, PubMed:7945388, PubMed:7953292, PubMed:9882430)。通过血脑屏障向大脑供应肌酸方面发挥重要作用 (By similarity)。 {ECO:0000250|UniProtKB:Q8VBW1, ECO:0000269|PubMed:17465020, ECO:0000269|PubMed:22644605, ECO:0000269|PubMed:25861866, ECO:0000269|PubMed:7945388, ECO:0000269|PubMed:7953292, ECO:0000269|PubMed:9882430}。

组织特异性

Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.

亚细胞定位

Cell membrane

关键词

3D-structure Alternative splicing Cell membrane Disease variant Glycoprotein Intellectual disability Ion transport Membrane Phosphoprotein Proteomics identification

外部链接

UniProt: P48029

NCBI Gene

GeneCards