钠依赖性多巴胺转运蛋白 (DA转运蛋白) (DAT) (溶质载体家族6成员3)
钠依赖性多巴胺转运蛋白 (DA转运蛋白) (DAT) (溶质载体家族6成员3)
Q01959功能描述
介导多巴胺的钠和氯依赖性转运 (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:39112701, PubMed:39112703, PubMed:39112705, PubMed:8302271)。亦介导去甲肾上腺素（亦称noradrenaline）的钠和氯依赖性转运 (By similarity)。光依赖性视网膜透明血管退行的调节因子，位于OPN5信号通路的下游 (By similarity)。 {ECO:0000250|UniProtKB:P23977, ECO:0000250|UniProtKB:Q61327, ECO:0000269|PubMed:10375632, ECO:0000269|PubMed:11093780, ECO:0000269|PubMed:1406597, ECO:0000269|PubMed:15505207, ECO:0000269|PubMed:19478460, ECO:0000269|PubMed:39112701, ECO:0000269|PubMed:39112703, ECO:0000269|PubMed:39112705, ECO:0000269|PubMed:8302271}。
组织特异性
Highly expressed in substantia nigra (PubMed:7637582). Expressed in axonal varicosities in dopaminergic nerve terminals (at protein level) (PubMed:17296554). Expressed in the striatum (at protein level) (PubMed:17296554).
亚细胞定位
Cell membrane
关键词