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SLC30A7 Q8NEW0

锌转运蛋白 7 (ZnT-7) (溶质载体家族 30 成员 7) (Znt 样转运蛋白 2)

蛋白质信息 (UniProt)

锌转运蛋白 7 (ZnT-7) (溶质载体家族 30 成员 7) (Znt 样转运蛋白 2)

Q8NEW0

功能描述

Zinc ion transporter mediating zinc entry from the cytosol into the lumen of organelles along the secretory pathway (PubMed:15525635, PubMed:15994300). 通过维持早期分泌途径内的锌离子稳态,调节碱性磷酸酶等酶的激活和折叠 (PubMed:15525635, PubMed:15994300)。 {ECO:0000269|PubMed:15525635, ECO:0000269|PubMed:15994300}.

组织特异性

Highly expressed in megakaryocytes and other bone marrow cells and in the epithelium of the small intestine. Expressed in testis (in Leydig cells), adrenal gland (in adrenal medula, zona fasciculata and zona of reticularis), and pituitary gland (in somatotropic cells).

亚细胞定位

Golgi apparatus membrane

关键词

3D-structure Cytoplasmic vesicle Golgi apparatus Ion transport Membrane Mitochondrion Proteomics identification Reference proteome Sarcoplasmic reticulum Transmembrane