SLC16A7 O60669

单羧酸转运蛋白 2 (MCT 2) (溶质载体家族16成员7)

功能描述

质子偶联单羧酸同向转运蛋白。催化单羧酸（如L-乳酸、丙酮酸和酮体、乙酰乙酸、β-羟丁酸及乙酸）跨越质膜的快速转运 (PubMed:32415067, PubMed:9786900)。二聚化是功能所必需的，且两个亚基在转运底物过程中协同工作 (PubMed:32415067)。 {ECO:0000269|PubMed:32415067, ECO:0000269|PubMed:9786900}。

组织特异性

Detected in heart and in blood lymphocytes and monocytes (at protein level) (PubMed:15505343). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and leukocyte (PubMed:9786900). Restricted expression in normal tissues, but widely expressed in cancer cells.

亚细胞定位

Cell membrane