SIGLEC6 O43699

唾液酸结合Ig样凝集素 6 (Siglec-6) (CD33抗原样1) (CDw327) (肥胖结合蛋白1) (OB-BP1) (CD抗原CD327)

功能描述

推定的粘附分子，介导依赖唾液酸的细胞结合。与α-2,6-连接的唾液酸结合。唾液酸识别位点可能被与同一细胞表面唾液酸的顺式相互作用所遮蔽。

组织特异性

Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.

亚细胞定位

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.