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SIGLEC12 Q96PQ1

唾液酸结合Ig样凝集素12 (Siglec-12) (唾液酸结合Ig样凝集素样1) (Siglec-L1)

蛋白质信息 (UniProt)

唾液酸结合Ig样凝集素12 (Siglec-12) (唾液酸结合Ig样凝集素样1) (Siglec-L1)

Q96PQ1

功能描述

功能:推定的粘附分子,介导依赖唾液酸的细胞结合。唾液酸识别位点可能被与同一细胞表面唾液酸的顺式相互作用所遮蔽。

组织特异性

Isoform Short is highly expressed in spleen, small intestine and adrenal gland; it is lower expressed in thyroid, placenta, brain, stomach, bone marrow, spinal cord and breast. Isoform Long is highly expressed in spleen, small intestine and bone marrow; it is lower expressed in thyroid, placenta, thymus, trachea, stomach, lung, adrenal gland, fetal brain and testis.

亚细胞定位

Membrane; Single-pass type I membrane protein.

关键词

Alternative splicing Cell adhesion Disulfide bond Glycoprotein Immunoglobulin domain Lectin Membrane Phosphoprotein Proteomics identification Reference proteome