SELENBP1 Q13228

甲硫醇氧化酶 (MTO) (EC 1.8.3.4) (56 kDa 硒结合蛋白) (SBP56) (SP56) (硒结合蛋白 1)

功能描述

催化甲硫醇的氧化，甲硫醇是一种已知由肠道细菌大量产生的有机硫化合物 (PubMed:29255262)。硒结合蛋白，可能参与感知细胞质中的活性异生物质。可能参与高尔基体内的蛋白质转运 (By similarity)。 {ECO:0000250|UniProtKB:Q8VIF7, ECO:0000269|PubMed:29255262}。

组织特异性

Widely expressed. Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients.

亚细胞定位

Nucleus