蛋白侧友-1
蛋白侧友-1
Q7Z5N4功能描述
一种黏附分子,促进视网膜内的层特异性突触连接。在特定亚型的中间神经元和视网膜神经节细胞(RGCs)中表达,并通过同嗜性相互作用促进突触连接。 {ECO:0000250|UniProtKB:Q8AV58}。
组织特异性
Up-regulated in glomeruli in HIV-associated nephropathy. In diseased glomeruli, significantly overexpressed and the expression is no longer restricted to mesangial cells but includes podocytes and parietal epithelial cells (PubMed:15213259).
亚细胞定位
Cell membrane
关键词