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RPL17 P18621

核糖体大亚基蛋白 uL22 (60S核糖体蛋白 L17) (60S核糖体蛋白 L23) (PD-1)

蛋白质信息 (UniProt)

核糖体大亚基蛋白 uL22 (60S核糖体蛋白 L17) (60S核糖体蛋白 L23) (PD-1)

P18621

功能描述

核糖体大亚基的组分 (PubMed:12962325, PubMed:23636399, PubMed:32669547)。核糖体是一个巨大的核糖核蛋白复合物,负责细胞内蛋白质的合成 (PubMed:12962325, PubMed:23636399, PubMed:32669547)。 {ECO:0000269|PubMed:23636399, ECO:0000269|PubMed:32669547, ECO:0000305|PubMed:12962325}。

组织特异性

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1.

亚细胞定位

Cytoplasm

关键词

3D-structure Alternative splicing Cytoplasm Diamond-Blackfan anemia Direct protein sequencing Proteomics identification Reference proteome Ribonucleoprotein Ribosomal protein