ROBO4 Q8WZ75

同源物4 (Magic roundabout)

蛋白质信息 (UniProt)

同源物4 (Magic roundabout)

Q8WZ75

功能描述

Slit蛋白的受体，至少针对SLIT2，似乎参与血管生成和血管模式形成。可能介导Slit蛋白对原代内皮细胞迁移的抑制（通过相似性）。参与内皮屏障结构和功能的维持（PubMed:30455415）。 {ECO:0000250, ECO:0000269|PubMed:30455415}。

组织特异性

Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta (PubMed:30455415).

关键词

Alternative splicing Angiogenesis Developmental protein Differentiation Disease variant Disulfide bond Glycoprotein Immunoglobulin domain Phosphoprotein Proteomics identification

外部链接

UniProt: Q8WZ75

NCBI Gene

GeneCards