RMDN3 Q96TC7

微管动力学调节蛋白3 (RMD-3) (hRMD-3) (脑蛋白10) (FAM82A2蛋白) (FAM82C蛋白) (蛋白酪氨酸磷酸酶相互作用蛋白51) (TCPTP相互作用蛋白51)

功能描述

参与细胞钙稳态调节。可能参与角质形成细胞的分化和凋亡。过表达诱导凋亡。 {ECO:0000269|PubMed:16820967, ECO:0000269|PubMed:22131369}。

组织特异性

Present at high level in epidermis and seminiferous epithelium: while basal cells in the epidermis and spermatogonia show no perceptible amount, keratinocytes of suprabasal layers and differentiating first-order spermatocytes up to spermatids exhibit high expression. In skeletal muscle, its presence is restricted to fibers of the fast twitch type. In surface epithelia containing ciliated cells, it is associated with the microtubular structures responsible for ciliary movement. Also present in specific structures of the central nervous system such as neurons of the hippocampal region, ganglion cells of the autonomic nervous system, and axons of the peripheral nervous system (at protein level). Widely expressed.

亚细胞定位

Mitochondrion outer membrane