RFPL1 O75677

Ret指蛋白样1 (RING指蛋白78)

蛋白质信息 (UniProt)

Ret指蛋白样1 (RING指蛋白78)

O75677

功能描述

负向调节G2-M期转换，可能通过促进cyclin B1/CCNB1和CDK1的蛋白酶体降解，从而阻止它们在间期的积累。 {ECO:0000269|PubMed:20725088}。

组织特异性

Seems to be expressed in prostate and less abundantly in adult brain, fetal liver, and fetal kidney.

亚细胞定位

Cytoplasm

关键词

Cell cycle Cytoplasm Metal-binding Nucleus Phosphoprotein Proteomics identification Reference proteome Zinc Zinc-finger

UniProt: O75677

NCBI Gene

GeneCards