RELT Q969Z4

肿瘤坏死因子受体超家族成员19L (淋巴样组织中表达的受体)

蛋白质信息 (UniProt)

肿瘤坏死因子受体超家族成员19L (淋巴样组织中表达的受体)

Q969Z4

功能描述

可能在细胞凋亡中发挥作用 (PubMed:19969290, PubMed:28688764)。过表达时，诱导MAPK14/p38和MAPK8/JNK MAPK级联反应的激活 (PubMed:16530727)。参与牙釉质形成 (PubMed:30506946)。 {ECO:0000269|PubMed:16530727, ECO:0000269|PubMed:19969290, ECO:0000269|PubMed:28688764, ECO:0000269|PubMed:30506946}。

组织特异性

Spleen, lymph node, brain, breast and peripheral blood leukocytes (at protein level) (PubMed:28688764). Expressed highly in bone marrow and fetal liver. Very low levels in skeletal muscle, testis and colon. Not detected in kidney and pancreas.

亚细胞定位

Cell membrane

关键词

Amelogenesis imperfecta Apoptosis Cell membrane Cytoplasm Direct protein sequencing Disease variant Disulfide bond Glycoprotein Membrane Phosphoprotein

外部链接

UniProt: Q969Z4

NCBI Gene

GeneCards