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RALGPS1 Q5JS13

Ras特异性鸟苷酸释放因子 RalGPS1 (含PH结构域和SH3结合基序的Ral GEF 1) (Ral鸟苷酸交换因子 2) (RalGEF 2) (RalA交换因子 RalGPS1)

蛋白质信息 (UniProt)

Ras特异性鸟苷酸释放因子 RalGPS1 (含PH结构域和SH3结合基序的Ral GEF 1) (Ral鸟苷酸交换因子 2) (RalGEF 2) (RalA交换因子 RalGPS1)

Q5JS13

功能描述

小GTPase RALA的鸟苷酸交换因子(GEF)。可能参与细胞骨架组织(By similarity)。鸟苷酸交换因子。 {ECO:0000250, ECO:0000269|PubMed:10747847, ECO:0000269|PubMed:10889189}。

组织特异性

Widely expressed (at protein level). Isoform 2 is expressed in brain, colon, kidney, pancreas, prostate, skeletal muscle, small intestine, testis, thymus and uterus. Isoform 1 is expressed at high levels in heart and testis and at lower levels in brain, pancreas, skeletal muscle, small intestine and thymus.

亚细胞定位

Cytoplasm

关键词

3D-structure Alternative splicing Cell membrane Cytoplasm Guanine-nucleotide releasing factor Membrane Proteomics identification Reference proteome