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POU6F2 P78424

POU结构域,第6类,转录因子2 (视网膜源性POU结构域因子1) (RPF-1)

蛋白质信息 (UniProt)

POU结构域,第6类,转录因子2 (视网膜源性POU结构域因子1) (RPF-1)

P78424

功能描述

可能的转录因子,可能参与无长突细胞和神经节细胞分化的早期步骤。识别并结合DNA序列5'-ATGCAAAT-3'。Isoform 1不结合DNA。

组织特异性

Expressed only within the CNS, where its expression is restricted to the medical habenulla, to a dispersed population of neurons in the dorsal hypothalamus, and to subsets of ganglion and amacrine cells in the retina.

亚细胞定位

Nucleus

关键词

Alternative splicing Disease variant DNA-binding Homeobox Nucleus Proteomics identification Reference proteome Transcription Transcription regulation